Alicia Masters as a spider-monster (Marvel Comics) - leaping

Spider monster hybridisation serum


This mutagenic serum was isolated by Professor Louis Kort, from London. It was an attempt at recreating the Jonathan Drew spider-serums by reverse-engineering them from Spider-Woman (Jessica Drew)’s organism.

It was synthesized in 1977. Agents of Hydra had mesmerized Spider-Woman and were holding Kort’s daughter as an hostage, to force the Professor’s hand.

Not only was it an imperfect brew, but it couldn’t have recreated Spider-Woman’s powers. Ms. Drew had received decade-long treatments by the High Evolutionary to make her what she is.


Powers & Abilities

Still, the serum could mutate Alicia Masters into a powerful spidery chimera. The documented abilities of this monster were:

  • Increased stature, plus fangs, digital claws and increased hair length and thickness.
  • Superhuman (probably “Class 10”) strength.
  • The ability to perform super-leaps.
  • Eight extra super-strong limbs (so that’s 12 total) making her highly mobile (for instance to climb buildings) and a very powerful wrestler.
  • Stingers at the end of these supplemental limbs, capable of injecting a powerful poison. This is her preferred method for killing.
  • Energy blasts from her hands, presumably similar to those of Spider-Woman, but even more powerful.
  • The ability to spin sticky webs with cable-like strands, using her mouth. She can also spit out an entangling stream of webbing.
  • Enhanced sense of hearing, allowing her to partially compensate for her blindness.

Her durability seemed high, but not superhuman. Sufficient small-arms fire might have been able to kill her. Had Ben Grimm been willing to hit her with enough force, he would likely have been able to quickly take her out.

Furthermore, her metabolism likely was unsustainable. She had a life expectancy measured in days or perhaps even hours.

If you are using our Leòn Genetic Sequence framework, it would make sense that only a person with a level of LGS activity can be mutated (Alicia is LGS-positive).


It seems that Hydra was never again able to duplicate the Kort serum. They only narrowly managed to grab one sample in the first place, as their operations were interrupted by the Thing and Shang-Chi.

Alicia Masters as a spider-monster (Marvel Comics) - face closeup

Alicia was incapacitated by Susan Storm-Richards after rampaging through central London and fighting the Thing and Spider-Woman. Professor Kort was able to undo the mutagenic effects and restore Alicia without any sequellae.

Back in a New York groove

Decades later, in 2011, Spider-Woman and the Thing fetched Ms. Masters so Dr. Richards could analyse her blood. Manhattan’s entire population was turning into spider monsters and/or getting spider powers.

Dr. Richards thought that analyzing Alicia’s immune system and how it had been affected by the Kort serum decades before might provide insight into curing Manhattanites. However, the organism of Eddie Brock in his Anti-Venom identity soon proved to be a more interesting lead.

Game Stats — DC Heroes RPG

Tell me more about the game stats

DEX 06 STR 09 BODY 06

Cling: 04, Directional hearing: 03, Enhanced Initiative*: 06, Energy blasts: 09, Extra Limbs (x8): 09, Growth: 01, Jumping: 06, Poison touch: 09, Running: 05, Snare: 08

Bonuses and Limitations:

  • Energy Blasts have a Continuing Effect (like Disintegration) but no AV.
  • Growth is Always On and Already Taken Into Account.
  • Poison Touch can be Combined with her EV from her Extra Limbs.
  • Running can be Combined With Cling.
  • Snare has a Range of but 2 APs but is Sticky.

Strange Appearance, Serious Rage, Misc.: the subject can only mindlessly lash out and follow orders from their handler (though it’s likely possible to roll to resist for a while).

Alicia was outfitted with a chip on her brow. The mini-video camera within:

  • could broadcast what was in front of her to the local Hydra HQ.
  • enabled Hydra agents to communicate with her via radio (though their control on her seemed shaky).
  • seemed to allow her to see (presumably via a cybernetic interface), but this is very tentative.

By Sébastien Andrivet.

Source of Character: Marvel Two-in-One Vol. 1 #31-32.

Helper(s): Darci, Pufnstuff.

Writeup completed on the 15th of June, 2016.